Glaucoma a clinico-experimental study of the effect of interaction of some anti-glaucoma drugs on the intraocular pressure

Many drugs are used in the management of glaucoma, each exerting its effect through a certain mechanism. The interaction of two or more of these drugs administered concomittently is of importance to the ophthalmologist. Such interaction may reduce the intraocular pressure [IOP], or may antagonize the intended therapeutic effect of any of them. The effect of pilocarpine, timolol, eserine and diamox, each alone and in different combinations was studied clinically in 149 eyes of chronic simple glaucoma, and experimentally in albino rabbits. The results showed that pilocarpine remains the most effective and safest topical drug for prolonged use in open angle glaucoma. The use of timolol is accompanied by two phenomena "the short term escape" and the "long term drift". Combining it with another drug after one year of its use is essential to keep its efficiency. Pilocarpine-acetazolamide is the most effective combination in reducing IOP compared to all other combinations

survey of some ophthalmic problems in hurghada

An organised survey of the inhabitants off Hurghada attending the outpatient clinic and of school children was carried out. Among the 300 outpatient clinic visitors, pterygium was searched for in adults and refractive errors in children below 15 years of age. Pterygium was found ion 5% of patients [15/300]. Of the 720 school children examined, a search for the different stages of trachoma and refractive errors was stressed upon. Two hundred and ninety two [292] children [40.56%] were affected with different stages off trachoma, while 112 [15.6%] had refractive errors. One hundred and thirty [130] persons were randomly selected to test for the incidence of toxoplasmosis, of them 15 persons [11.54%] gave positive results